Wissam Ben Yedder opened the scoring for Lyon in the first minute. Lyon equalized through Alexandre Lacazette in the 38th minute.
Rayan Cherki made it 3-1 in the 78th minute for the hosts. Lyon move up to 7th in Ligue 1, one point behind Rennes (6th) who will play Sunday in Ajaccio. ASM (4th) is eight lengths behind OM (3rd) but five points ahead of Losc (5th)