China News Network, Guangzhou, June 22 (Cai Minjie, Zhang Yang) Sun Yat-sen Memorial Hospital of Sun Yat-sen University said on the 22nd that the thyroid cancer gene test was written by Li Honghao, director of the thyroid surgery department of the hospital, and Ouyang Nengtai, deputy director of the Center for Cellular Molecular Diagnostics. Guangdong Expert Consensus (2020 Version) with Clinical Application has been released.
Unlike the traditional diagnosis and treatment model of thyroid nodules, the above-mentioned "consensus" involves precise diagnosis and individualized treatment plan development, and formulates precise individualized management plans for patients with thyroid tumors. The content includes genetic testing to determine the benign and malignant thyroid nodules and individuals. Chemotherapy, genetic thyroid cancer screening and targeted therapy, as well as how to do genetic testing, which genes to detect, etc.
Thyroid cancer is the fastest growing malignancy in recent years. According to data released by the National Cancer Center, the incidence of thyroid cancer among women in urban areas in the mainland ranks fourth among all malignant tumors in women. Thyroid cancer has different malignant degrees and different treatment methods. Understanding the pathogenesis of thyroid cancer from the genetic level of the tumor, screening low-risk thyroid cancer and high-risk thyroid cancer, and establishing an accurate, standardized, and individualized management model may become the general trend.
Li Honghao introduced that with the increase of people's health checkup awareness, more and more small thyroid papillary carcinomas are found, but "small cancer" does not mean "low-risk cancer", the strong invasive small cancer has occurred in the early stage of the neck Cases of lymphatic metastasis are not uncommon. For small papillary thyroid cancer, there are currently multiple treatment options including active observation, ablation, and surgery. Among them, the range of thyroid cancer surgery with different degrees of malignancy is different.
"Thyroid cancer needs to adhere to the principles of "early prevention, early detection, and early treatment." Li Honghao said that the release of the "Consensus" is a clinical work to find a reasonable thyroid cancer evaluation method and accurately judge low-risk or high-risk thyroid cancer. The difficulty is meaningful.
"In thyroid cancer, most benign nodules do not require surgical treatment, and excessive surgery caused by inaccurate screening will bring many disadvantages such as lifelong medication. Genetic testing can help accurately identify the benign and malignant thyroid nodules, Let patients avoid excessive treatment and also take into account the standardization and radical cure." Ouyang Nengtai said, in addition, genetic testing can accurately screen out hereditary thyroid cancer, hereditary medullary thyroid cancer is relatively malignant, and early screening of asymptomatic genes Mutant patients, early and timely treatment, can save the patient's life.
Ouyang Nengtai said that compared with other malignant tumors, genetic testing is usually performed after surgery, and thyroid genetic testing is usually performed before surgery. Its main purpose is to identify the benign and malignant thyroid nodules and assess the tumor's ability to invade, and ultimately decide whether it is needed. Surgery and scope of surgery. (Finish)