<Anchor>

Of course, this is good news, but there are still many steps to be taken before vaccines can be returned to real people.

Today (19th), after looking at the report of a medical journalist Cho Dong-chan, we will answer more questions about the significance of the clinical trial results from the United States and what course to take in the future.

<Reporter> If you get a

virus or get a vaccine, there are several types of antibodies.

There are good antibodies that interfere with the cell's penetration of the virus, but some have no role or, rather, bad antibodies that help the virus penetrate cells well.Of these, good antibodies that block viruses are called neutralizing antibodies, but the effectiveness of the vaccine depends on how many neutralizing antibodies are produced.

U.S. Modena vaccines confirmed the first neutralized antibodies in 8 out of 45 participants.

The vaccine is considered successful as the first step in a clinical trial because it has proven that it can block the Corona19 virus.

However, the amount of neutralizing antibodies has not been determined enough, and safety has not been verified.

In some cases, when a person who is vaccinated is exposed to a virus, more bad antibodies are produced than good neutralizing antibodies, and dengue fever vaccines have been banned for this reason.

[Song Man-gi / Deputy Director, International Vaccine Research Institute: Safety has not been verified. Later, when the virus actually got infected or even when it was necessary to prove its safety, commercialization still seems to be distant.] In

subsequent clinical trials, it is not possible to succeed in commercialization until it is confirmed that sufficient neutralizing antibodies are produced and there are no side effects that make the virus more susceptible .

(Video Editing: Jongwoo Kim)

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<Anchor>

Let's continue talking to Cho Dong-chan, a medical journalist.

Q. Compared to other vaccines in development worldwide?

[Cho Dong-chan / Medical journalist (specialist): There are 8 vaccine clinical trials reported to the World Health Organization, 4 in China, 2 in the US, and 1 in the UK and Germany. In fact, the most important thing in the academic world is the UK vaccine. This is because the world's largest 880 people are exempt from toxicology trials and are conducting clinical trials so that safety and effectiveness can be seen the fastest.

It is the first time that a US moder or vaccine has demonstrated neutralizing antibodies, but it has not yet been officially reported, but the Chinese vaccine has also been known to confirm neutralizing antibodies. No vaccine can be commercialized yet, but at present, the UK and US vaccines are considered to be the most advanced.]

Q. Which vaccine is advantageous for us?

[Cho Dong-chan / Medical journalist (specialist): It would be better to get a safe and effective vaccine quickly from any country. However, assuming that it is equally safe and effective, a British vaccine may be advantageous. The patented Jenner Institute at Oxford University in the UK has rejected multinational companies' claim for monopoly and is transferring technology to six countries around the world. I don't think there's any thought to make a lot of money from vaccines, whereas Modena says that American companies have monopoly and RNA vaccines, so mass production is not easy. If this is successful, it means that a significant strategy may be needed to secure a vaccine. However, there will be variables depending on cooperation among countries.]

Q. What is the status of clinical trials in Korea?

[Cho Dong-chan / Medical journalist (specialist): I'd like to do other clinical trials for other American vaccines next month, so I don't know what will succeed. This is because the final successful product can be utilized as soon as possible in Korea.]   

▶ "Formation of antibodies for all clinical participants"… Corona19 vaccine green light?