The 24-year-old tennis player from Moscow was defeated in the 1/4 final match by the American Francis Tiafoe with a score of 0:3.
The game lasted 2 hours and 37 minutes.
On account of the Russian 14 aces and one double fault.
The American has 17 innings and three double faults.
US Open 2022 runs from August 29 to September 10.
The total prize fund of the competition is $60 million.
Previously, the fourth racket of the world, 19-year-old Spanish tennis player Carlos Alcaras, beat Croat Marin Cilic in the fourth round of the US Open and set a new record in the Open Era.