The 26-year-old tennis player from Russia lost in two sets with a score of 3:6, 2:6 to the Spaniard Roberto Bautista-Agut in the 1/4 finals of the playoffs.
The game lasted 1 hour 10 minutes.
The next opponent of the Spanish tennis player will be the winner of the match between the Swiss Antaun Bouillet and the representative of the Netherlands Tallon Grikspur.
The tournament in Mallorca belongs to the ATP 250 category and is held on grass.
The total prize fund is about $900,000. The current champion of the tournament is Medvedev.
Earlier it was reported that Russian Daria Kasatkina failed to reach the semi-finals of the Women's Tennis Association (WTA) tournament in Bad Homburg, Germany.