The Belgian race car driver posted a time of 1:14.127.
Ferrari drivers Charles Leclerc (+0.081) and Carlos Sainz (+0.225) came in second and third respectively.
Seven-time Formula 1 champion Lewis Hamilton (Mercedes) is 13th (+1.294).
The ninth stage of the World Championship takes place in Montreal on the track named after Gilles Villeneuve.
Earlier it was reported that Verstappen became the best in the first practice of Formula 1 - the Canadian Grand Prix.