The 23-year-old tennis player beat Laura Siegemund 7:5, 6:3 in the quarterfinals.
The duration of the meeting was 1 hour 48 minutes.
The next opponent of Samsonova will be the winner of the pair Iga Swiatek (Poland) - Emma Radukanu (Great Britain).
The prize fund of the tournament is about €610,000.
Earlier it was reported that Russian Anastasia Potapova made it to the semifinals of the WTA tournament in Istanbul.