Away at the Alfredo di Stéfano Stadium, the reigning Champions League champions Barcelona won 3-1 against tournament debutant Real Madrid.
Olga Carmona surprisingly gave the home team the lead over league leaders Barca - but in the second half, the Catalan club, which so far has won all 24 matches in the league and already secured that title, turned around.
In the hunt for the next, Alexia Putellas equalized from the penalty spot, and at the end of the second half, Alexia Putellas completed the turnaround when she took advantage of an opposition in the penalty area and placed 2-1.
Where since the final result was 3-1 to the guests, Putellas became a two-goal shooter in extra time when she nicely chipped over goalkeeper Misa.
Asllani away
National team striker Fridolina Rolfö played the entire match for Barcelona, but Kosovar Asllani was missing from Real Madrid due to injury.
The quarter-final return will be decided on March 30.