At home at Old Trafford, Manchester United lost 0-1 to Wolverhampton after a late goal by João Moutinho.
The Portuguese scored the decisive goal after midfielder Phil Jones from the penalty area nodded a post straight to him.
The 29-year-old started in his first Premier League match since January 2020, as Victor Lindelöf, as well as Eric Bailly and Harry Maguire were missing.
Jones was one of the team's best players in the first half, but the mistake was costly.
The text is updated.