The Russian woman finished with a score of 02: 36.41.
Her compatriot Tatyana Sorina finished sixth (+7.53).
The top three also includes Swedish Johanna Hagström (+0.32) and Finnish Johanna Matintalo (+0.86).
Recall that the Russian men were unable to reach the final of the stage race.
Tour de Ski - 2022 runs from December 28 to January 4 in Switzerland, Germany and Italy.
Earlier Sorina and Nepryaeva reached the final of the "Tour de Ski" sprint in Oberstdorf.