Nepomniachtchi defeated Pole Jan-Krzysztof Duda and US representative Timur Gareev, and also tied with Baadur Jobava from Georgia and Israeli Boris Gelfand.
Among other Russians, Alexander Grischuk and Kirill Alekseenko also scored three points each.
In addition, Sergey Karjakin scored 3.5 points, Daniil Dubov - 2.5 points, Vladimir Fedoseev - two points.
Thus, the second place is shared by Nepomniachtchi, Grischuk and Nodirbek Abdusattorov from Uzbekistan, who have seven points each.
The leader is the current holder of the chess crown, Norwegian Magnus Carlsen (7.5).
Earlier it was reported that Nepomniachtchi scored four points on the first day of the World Rapid Chess Championship.