The meeting took place in Watford and ended in favor of the guests - 3: 1.
As part of the Citizens, Raheem Sterling scored in the fourth minute, and Bernardo Silva scored a double in the 31st and 63rd minutes.
The only goal of the hosts was scored by Cucho Hernandez (74th minute).
For Josep Guardiola's charges, this victory was the fifth in a row in the English Football Championship.
City scored 35 points and climbed to first place in the national championship standings.
Watford (13 points) are in 17th place.
Earlier it was reported that Divock Origi's goal brought Liverpool a victory over Wolverhampton in the Premier League match.