Tottenham, replaced by Son Heung-min, suffered a shocking loss to Mura, who is considered underdog in the Europa Conference League.
Slovenia Mura, away Tottenham Hotspur started a large number of candidates considering the weekend league match, but they conceded the opening goal in the 11th minute of the first half.
He was hit by a left-footed shot from the opposing Horbart.
To make matters worse, Tottenham were outnumbered by Sessegnon's red card in the 33rd minute of the first half, and Conte, who became urgent, replaced four players including Son Heung-min in the 9th minute of the second half.
Tottenham after Kane equalized in the 27th minute of the second half, they continued to knock on Mura's goal but could not open it.
Rather, he conceded a goal in extra time in the second half and suffered a shocking defeat.
Tottenham Hotspur maintained their second place in the group, but failed to advance to the round of 16 as group first became impossible.