In the Europa Conference League, Tottenham fell to third place in the group after losing to Vitesse of the Netherlands, excluding key players such as Son Heung-min and Kane.
Santo did not accompany key players such as Son Heung-min and Kane on the away road in preparation for the weekend league game, but Tottenham were helpless without 'cha-po'.
Seven shots were less than half of the opponent's, and Brian Hill's best shot from long range hit the post like this.
Tottenham eventually scored the winning goal in the 33rd minute of the second half and lost 1-0.
They fell to 3rd place from the top of the group and were in danger of being eliminated from the group stage.
The BBC pointed out that Tottenham paid the price for leaving stars such as Son Heung-min at home.