The match at Stamford Bridge was not only a clash between two major teams in the Premier League but also a replay of the Champions League final earlier this year.
Then Chelsea won 1-0 - today the roles were reversed.
Visiting Manchester City owned much of the game in a poor first half.
One of the better positions came in the 40th minute.
A post from the left reached Gabriel Jesus who with a good first touch with his chest created space in the penalty area.
However, the finish did not hold the same class and slipped a good distance outside the goal.
Released the first goal of the season
However, things went better at the beginning of the second half.
After a short corner variant, the ball ended up with a heavily courted Jesus who, despite three men around him, managed to turn around and get to a finish.
The shot was controlled, via Chelseaben, in goal and meant 1-0 for City in the 53rd minute.
Thus, Chelsea have conceded the season's first game goal.
If the first half was poor chance, the second was the opposite.
Both teams created several good situations and Chelsea also had a ball in goal.
However, the goal was correctly ruled out for offside.
With seven minutes left of regular time, Jack Grealish punctured the match.
The City striker was first on a ball in the deep but failed to poke the ball past Édouard Mendy in goal.
There were no more goals in the match and City collected three points.
For Chelsea, who before the meeting had four wins and one draw, it was the first loss of the season.