The meeting lasted 1 hour 44 minutes and ended with the defeat of Rublev in two sets with a score of 5: 7, 6: 7.

In the next round, Isner will play against the winner of the pair Gaelle Monfils (France) - Francis Tiafoe (USA).

Earlier, Khachanov lost to Tsitsipas in the 1/8 finals of Masters in Toronto.