Granada made it to the group stage of the Europa League by defeating Malmö FF in the playoffs.
Now they are facing the toughest possible opposition when it comes to meeting the English league runners-up Manchester United.
Dinamo Zagreb, who yesterday beat and beat Tottenham in the round of 16, will face Spanish Villarreal.
A Europa League title provides a direct place to the next edition of the Champions League and can thus be important for those clubs that do not reach the Champions League via their domestic league.
The quarter finals will be played on April 8 and 15.
The semifinals on April 29 and May 6.
The final will be played in Gdansk, Poland on May 26.