The meeting, which took place at the Dragão stadium in Porto, ended with a score of 2: 1 in favor of the hosts.
Mehdi Taremi and Moussa Marega scored goals for the Portuguese club.
The only goal of the hosts on account of Federico Chiesa.
The return match will take place on March 9 in Turin.
Earlier it was reported why the first matches of the 1/8 finals of the Champions League are interesting.