The meeting, which took place in Vienna, ended with a score of 2: 1 in favor of the guests.
Rapid scored first.
On the 51st minute, Taxiarchis Funtas scored, assisted by Ercan Kara.
The victory for Arsenal was brought by goals from David Luis and Pierre-Emerick Aubameianca, who scored in the 70th and 74th minutes with passes by Nicolas Pepe and Hector Bellerin, respectively.
In the second round, Arsenal will host the Irish Dundalk at home, while Rapid will play away with the Swedish Molde.
Earlier it was reported that "Napoli" lost to AZ in the Europa League match.