The meeting lasted 1 hour 35 minutes and ended with a score of 6: 1, 6: 4, 6: 2 in favor of the second racket of the world.
Ito takes the 146th place in the ranking of the Association of Professional Tennis Players (ATP).
In the third round, Djokovic will play with another representative of Japan, Yoshihito Nishioka, who defeated Briton Daniel Evans.
Djokovic is the current winner of the Australian Open.
Earlier it was reported that Ekaterina Alexandrova entered the third round of the Australian Open, in which she would play with Petra Kvitova.