According to the Zenit press service, the French team Lyon will be the first rival of the team. The first game will take place on September 17. On October 2, a match with Portuguese Benfica will take place in St. Petersburg, and on October 23 - away from RB Leipzig. On November 5, Zenit will play again with the German team, but already in their own fields, and on November 27 at the Gazprom Arena will receive Lyon. The final match of the group stage will be held on December 10 in Lisbon on the Benfica field.

Lokomotiv will play its first match on September 18 away from the German Bayer. The second will be a game with Madrid Atletico, which will take place on October 1 at the Russian Railways Arena. On October 22, Lokomotiv will play with Juventus in Turin, and on November 6, an Italian grand in Moscow will play a return game with railway workers. On November 26, a game with Bayer will be held at the Russian Railways Arena, and on December 11 Lokomotiv will play against Atletico at Vanda Metropolitano.

Previously, all the participants in the group stage of the Europa League were determined.