The meeting, held in Rostov-on-Don, ended with the score 2-1 in favor of the home team.
Victory "Rostov" brought the goals of Eldor Shomurodov and Alexei Ionov. In the "Orenburg" distinguished George Despotovich.
The rival of Rostov in the second round will be Spartak, and Sochi will play against CSKA. Matches will be held July 20.
Earlier it was reported that Moscow "Spartak" defeated "Sochi" in the first round match of the RPL.