The meeting, held in Moscow, ended with the score 5-2 in favor of the owners of the ice.
The victory of CSKA brought the puck Alexey Marchenko, Andrei Svetlakov, and Mikhail Grigorenko designed a hat-trick.
Avangard responded with Victor Stolberg and Sergey Shumakov goals.
Account in the series was 1-0 in favor of CSKA. The second game will be held in Moscow on April 15.
Earlier, Alexander Kozhevnikov expressed the opinion of the confrontation of CSKA Moscow and Omsk Avangard in the Gagarin Cup final.