Manchester City won the first leg of the round of 16 against FC Copenhagen 3:1 (2:1) It was City's eleventh win in a row across all competitions. Kevin De Bruyne was directly involved in all of the goals.

The second leg will take place on March 6th in Manchester. The English champions traveled to the Danish capital as the high favorite. FCK defeated City's local rivals Manchester United and Galatasaray Istanbul in the group stage at the Parken Stadium.