RB Leipzig lost 0-1 (0-0) in the first leg of the round of 16 against Real Madrid. Brahim Díaz scored the goal for the away win for the eight-time Champions League winners in the 49th minute.

The second leg will take place on March 6th in Madrid. The game started with an extremely questionable offside decision. The Bundesliga club played courageously forward at times, but without creating any great chances. Jan Šeško had the best chance to equalize in the 82nd minute.