Scientists from the Institute of Experimental Medicine of the Federal State Budgetary Institution “National Medical Research Center named after V.A.
Almazov, First St. Petersburg State Medical University named after Academician I.P.
Pavlova and St. Petersburg State University found that taking fermented milk products enriched with probiotics helps speed up the recovery of the heart after a heart attack.
The study was supported by a grant from the Russian Science Foundation (RSF).
The results are published in the journal Microorganisms.
Experiments on laboratory rats have shown that taking probiotics and normalizing the intestinal microflora can accelerate the recovery of heart muscle damaged as a result of myocardial infarction.
Scientists used rodents with disturbed intestinal microflora in experiments.
Initially healthy rats served as the control group.
Then all animals were artificially provoked by a heart attack.
Some rats with disturbed microflora began to receive probiotics as part of dairy products.
Other rodents of this group, as well as initially healthy rats from the control group, did not receive probiotics.
As a result, it turned out that in rats treated with probiotics, recovery after a heart attack was faster than in animals from both control groups - both the one in which the rodents did not initially suffer from intestinal biome disorder, and the group that had a violation of the microflora, but did not receive probiotics. .
Necrosis of heart tissue as a result of myocardial infarction
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The experiment lasted 15 days.
As a result, it turned out that the area of necrosis of the heart muscle caused by a heart attack became 10% less in rats from the first group than in other animals.
Scientists attribute this effect to the fact that the improvement of the intestinal microflora led to a decrease in the overall level of inflammation in the body.
This helped speed up the healing of damaged heart tissue.
“Evolutionarily adapted probiotic microorganisms have a vital interest in maintaining a mutually beneficial relationship with the host.
Probably through the fine regulation of anti- and pro-inflammatory signaling molecules that are out of balance during systemic inflammation, probiotic bacteria protect heart muscle cells from both toxic damage and the effects of oxygen starvation, ”the project leader, Doctor of Medical Sciences, explained in a comment to RT , Professor and Corresponding Member of the Russian Academy of Sciences, Director of the Institute of Experimental Medicine of the Federal State Budgetary Institution “National Medical Research Center named after V.A.
Almazov" Mikhail Galagudza.
According to scientists, the results obtained allow us to begin the selection of probiotics for patients with a cardiological profile, as well as functional food products with therapeutic and prophylactic properties.
Recall that probiotics are live microorganisms that are part of a healthy intestinal microflora.
In case of violations of the microflora, probiotics can be prescribed in the form of drugs, as well as ingested with food.