The European Commission (EC) has approved Microsoft's acquisition of Bethesda parent company ZeniMax, according to a post on the EC's website.
Microsoft deposits 7.5 billion dollars (about 6.3 billion euros) for ZeniMax.
With ZeniMax, Microsoft will acquire game studio Bethesda, among others.
The company makes game series such as
The Elder Scrolls
The acquisition was announced in September last year, but has yet to be approved by regulators in Europe and the United States.
The American stock market watchdog SEC already approved the takeover last week.
The EC has also given its approval in the meantime.
It is not known whether the commission imposes further conditions on the purchase by Microsoft.
Bethesda Vice President Pete Hines said little would change at the company.
"We are still working on the same games, at the same studios that have been doing that for years. We will also continue to publish the games ourselves."
It is unknown whether Bethesda games will now exclusively appear on Xbox and PC.
Bethesda games will in any case be added to Microsoft's subscription service Game Pass.