The Russian beat the American Brandon Nakashima.
The meeting ended with the score 7:5, 7:5.
The game lasted 1 hour 37 minutes.
In the next round, the 38th racket of the world will fight the winner of the pair Alex Molchan (Slovakia) - Diego Schwartzman (Argentina).
The prize fund of the tournament is $6.3 million.
Earlier it was reported that Russian tennis player Veronika Kudermetova reached the second round of the WTA-1000 category tournament in Cincinnati.