Real Madrid suffered a painful and memorable home defeat in Spanish football's Clásico against arch-rivals FC Barcelona.

The "Royal" around the former German world champion Toni Kroos and the former Bayern defense chief David Alaba lost 0: 4 (0: 2) on Sunday evening in the venerable Estadio Santiago Bernabéu.

With two goals, the former Bundesliga professional Pierre-Emerick Aubameyang (29th minute and 51st) made a significant contribution to the prestigious success for the financially troubled Catalans, who even had to part with their icon Lionel Messi before the season.

National goalkeeper Marc-Andre ter Stegen spent a rather quiet evening in the goal of the guests against completely disappointing hosts.

Without the injured goalscorer Karim Benzema, the offensive of the Madrilenians, who played all in black this time, achieved almost nothing.

Ronald Araujo (38') and Ferran Torres (47') scored the other goals for Xavi Hernandez's side, who will face Eintracht Frankfurt in the quarter-finals of the Europa League.

Barça last won 4-0 at Real Madrid in November 2015.

The club had not managed to win in the past six classics.

In the table, Real remains under coach Carlo Ancelotti with 66 points ahead of Sevilla FC (57), who had only played 0-0 at home against Real Sociedad San Sebastián before Real lost.

FC Barcelona is third, level on points with Atlético Madrid.

Meanwhile, English football champions and leaders Manchester City and Premier League pursuers Liverpool FC meet in the semi-finals of the FA Cup.

Man City, who last won the trophy three years ago, beat Southampton FC 4-1 (1-1) in the quarter-finals on Sunday.

Liverpool made the semi-final hit a little later with a narrow 1-0 (0-0) at second division club Nottingham Forest.

Diogo Jota (78th) scored the winning goal in Nottingham for coach Jürgen Klopp's team, who now have to play away at City and star coach Pep Guardiola on April 16th.

Already on April 10, the two rivals will play against each other in the Premier League, where Liverpool are only one point behind City.

Raheem Sterling (12'), Kevin De Bruyne (62') from the penalty spot, Phil Foden (75') and Riyad Mahrez (78') shot the Cityzens into the next round in Southampton.

A professional from Man City also scored the goal for the hosts.

An own goal by Aymeric Laporte (45+2) led to an equalizer for the Saints.

Everton FC had previously experienced a cup debacle at Crystal Palace.

Coach Frank Lampard's team, who are in danger of relegation and are 17th in the Premier League table, lost clearly 4-0 (2-0) in London and can now devote themselves entirely to the fight to stay in the class.

On the other hand, Palace will contest the other semi-final on April 16 at Champions League winners and club world champions Chelsea.

Chelsea advanced to the next round of the cup competition on Saturday.

The club from London, which is up for sale and has been subject to severe sanctions by the British government because of its Russian owner Roman Abramowitsch, had won 2-0 (2-0) at second division club FC Middlesbrough.

Romelu Lukaku (15th) and Hakim Ziyech (31st) scored for the team coached by Thomas Tuchel.

Meanwhile, the star ensemble from Paris Saint-Germain received the next embarrassment.

The team around world champion Kylian Mbappé and Brazil star Neymar lost 0: 3 (0: 1) at AS Monaco in the French Ligue 1 on Sunday through a goal by German international Kevin Volland.

The fourth defeat of the season hasn't had a major impact on PSG given their comfortable lead in the league, but the pressure on those responsible is likely to increase after the disappointments of the past few weeks.

"It's hard to say anything about that.

We started the game in the worst possible way," said PSG coach Mauricio Pochettino.

“It is unacceptable to start like this.

That was the main reason for the defeat.” Above all, you have to talk about the morale of the team in the first half.

Captain Wissam Ben Yedder with two goals (25th/84th, penalty kick) and Volland (68th) shot out the victory for the Monegasque.

Substitute Volland also took the penalty.

In the goal of the hosts, Alexander Nübel was not challenged too often.

Six-time world footballer Lionel Messi was absent from PSG due to flu symptoms.

Neymar disappointed and was substituted for Julian Draxler in the second half.

Paris had failed in the Champions League round of 16 after a slump in the second half at Real Madrid and had to give up their dream of the cup with handle again.

In the cup, Pochettino's team was knocked out by OGC Nice.