The seven-time F1 champion completed 50 laps the fastest.
Second place went to Max Verstappen of Red Bull, Netherlands, 11.825 seconds back.
The top three were closed by Hamilton's Mercedes partner Finn Valtteri Bottas (+27.531).
Thus, Hamilton and Verstappen equalized on points (369.5) and share the first place in the individual competition.
Now the champion of the 2021 season will be determined in the last stage - the Abu Dhabi Grand Prix (December 10-12).
Earlier it was reported that Russian Haas racer Nikita Mazepin had an accident in a race at the Saudi Arabian Grand Prix and retired.