With PSV Eindhoven in the Europa League, coach Roger Schmidt had to accept another setback.
The Dutch top club did not get past 0-0 at AS Monaco, which was overseen by the former Bundesliga coach Niko Kovac.
PSV, in which Philipp Max played through and Mario Götze was ill, has to fear for progress as third in Group B.
It is better for Monaco, which was also unbeaten in the fourth game of the current competition.
The team around EM participant Kevin Volland and goalkeeper Alexander Nübel leads the table.
The German coach Markus Gisdol recorded a respectable success in his second Europa League game with his new club Lokomotiv Moscow.
At Galatasaray Istanbul, the Russian club fought 1: 1 (0: 1), Moscow's goal scorer Francois Kamano (73rd) was substituted on by Gisdol shortly before the goal.
In Eintracht Frankfurt's group D, Fenerbahce Istanbul could meanwhile rely on its German professionals.
At 3-0 (3-0) at Royal Antwerp, Max Meyer (16th) and U21 European champion Mergim Berisha (29th) scored their first victory in the current competition.
Istanbul will presumably fight a duel with Olympiacos Piraeus for second place in the table, the Frankfurters are already well ahead.
This also applies to Bayer Leverkusen, which leads Group G before Betis Sevilla.
Leverkusen's next opponent, Celtic Glasgow, wins 3-2 (2-1) at Ferencvaros Budapest in the evening.
For the Hungarian club, which is looked after by the former Cologne Bundesliga coach Peter Stöger, it was the fourth bankruptcy in the fourth game.