Real Sociedad leads their first match in the Europa League group stage, but it was the Dutch who took the lead.
Former superstar Mario Götze, who decided the 2014 World Cup final for his Germany, put 1-0 in the 31st minute.
Shortly afterwards, Adnan Januzaj equalized for the Basques and then Isak made it 2-1 from close range.
The match is in progress.