The meeting took place in Pamplona and ended in favor of the guests - 4: 1.
Maxi Gomez, Gonçalo Gedes, Omar Alderete scored for the bats, and the hosts' defender Aridane Hernandez sent the ball into his own net.
The only goal for the local team was scored by Hon Moncayola.
Valencia's Russian midfielder Denis Cheryshev came out in the starting lineup, but due to an injury he was substituted in time compensated for the first half.
Valencia scored ten points and topped the Spanish Championship standings.
Osasuna (4) is on the 10th line.
Earlier it was reported that Cheryshev was injured.