Former world champion Mario Götze missed the Champions League million game with the Dutch football club PSV Eindhoven.
Coach Roger Schmidt's team couldn't get past a 0-0 draw against Benfica Lisbon on Tuesday evening and couldn't make up for their 2-1 defeat in the first leg.
The guests from Portugal had to make do with ten players for around an hour after yellow-red against Lucas Verissimo (32nd minute).
Mario Götze was in the starting line-up and played through 90 minutes.
Instead of back in the premier class group stage for the first time in three years, PSV is now competing in the Europa League.
Former Schalke coach David Wagner made the leap into the Champions League with the Young Boys.
After the 3: 2 in the first leg against Ferencvaros Budapest, the Swiss series champions also prevailed 3: 2 (2: 1) in Hungary.
Cedric Zesiger gave the boys an early lead (4th).
Henry Wingo (18th) and Ryan Mmaee (27th) turned the game around before the break.
Christian Fassnacht (56th) and Felix Mambimbi (90th + 3) then shot the Wagner team to victory.
Hungarians, trained by former Bundesliga coach Peter Stöger, have to console themselves with the Europa League.
In addition, the Swedish club Malmö FF prevailed against Ludogorez Razgrad.
After a 2-1 defeat in the first leg, the Swedes won 2-0 in the second leg.
Veljko Birmancevic (26th) and Jo Inge Berget (61st) scored the goals.
On Wednesday, among other things, the return legs of AS Monaco with coach Niko Kovac are due.
In the first leg his team lost 1-0 to Donetsk.