The meeting ended with a score of 2: 1.
At the 13th minute, Danny Welbeck brought the guests ahead.
The Mancunians responded with goals from Marcus Rashford and Mason Greenwood in the 62nd and 83rd minutes.
Manchester United scored 60 points and is ranked second in the England Championship standings.
Brighton (32) is in 16th position.
Tottenham previously drew with Newcastle in the Premier League.