Lyon are chasing their sixth straight Champions League title but may be forced to do so with a weakened squad as covid-19 entered the squad.
The PCR tests taken on Monday morning, before the quarter-final return against PSG, showed four new positive covid-19 cases in the women's squad.
These are in addition to the two that were discovered at the end of last week ", Lyon writes in a statement.
Given that the local health authorities are calling on the whole squad to be isolated, Lyon have asked Uefa to postpone the match.
Lyon won the first meeting with their French rival 1-0 away after a late penalty goal by veteran Wendie Renard.