The Clippers had otherwise started the season brilliantly with two straight victories, including over the local rival and the reigning champion team LA Lakers in the premiere, so there was no indication that such a breakthrough would come in their own home arena Staples Center.
However, the team's superstar Kawhi Leonard was missing, who had to sew eight stitches in her mouth after Friday's win against Denver.
The previous half-time record was 47 points and was recorded between Golden State and Sacramento in 1991.
The match is in progress.