The meeting, which took place in Moscow at the Russian Railways Arena, ended with a score of 2: 1 in favor of the home team.
The victory for Lokomotiv was brought by the goals of Vitaly Lisakovich and Vladislav Ignatiev, who scored at the 25th and 55th minutes of the meeting with the passes of Vedran Chorluka and Anton Miranchuk, respectively.
Khimki responded with a goal from Kirill Bozhenov, who scored in the 46th minute with a pass from Ilya Kukharchuk.
Lokomotiv scored 18 points and moved up to fourth place in the RPL standings.
Khimki with six points is in 14th position.
Earlier it was reported that Spartak and Zenit drew in the RPL match.