Tom Dumoulin will start in the Walloon Arrow on Wednesday.
The Jumbo-Visma rider would actually let the semi-classic go, he said on Sunday after the road race at the World Cycling Championships.
Egan Bernal is missing.
Dumoulin wanted to take some rest and prepare for the Amstel Gold Race on October 10.
"It has been enough for now," he said after he turned fourteenth at the World Cup in Imola.
The Limburger has now chosen to ride the Flèche Wallonne.
At Jumbo-Visma he will be joined by fellow countrymen Lennard Hofstede and Tom Leezer, the Belgian Laurens De Plus, the Dane Jonas Vingegaard and the German Paul Martens.
In Liège-Bastogne-Liège, which will be held on Sunday, Jumbo-Visma will be at the start with the same team, plus Primoz Roglic, who recently missed the overall victory in the Tour de France and finished sixth in the battle for the world title.
Bernal probably still has too much back pain
Bernal was on the provisional entry list, but he is not part of the final INEOS Grenadiers roster.
He probably still has too much trouble with his back, so he had to give up in the Tour and thus lost his title.
INEOS Grenadiers are betting in the Flèche Wallonne against Michal Kwiatkowski, who is in good shape, supported by Michał Gołaś, Ethan Hayter, Sebastian Henao, Iván Sosa and Cameron Wurf.
The victory in the Flèche Wallonne, which covers more than 200 kilometers and has ten climbs, went to Julian Alaphilippe in the past two years.
The brand new world champion is absent this year, however, because he is too tired.
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See also: The new 2020 cycling calendar for men and women