The meeting, which took place in German Duisburg, ended with a score of 2: 0 in favor of the Spanish team.
Sevilla's victory was brought by goals from Sergio Regilon and Youssef En-Nesseri, who scored in the 21st and 44th minutes with the assists of Ever Banega and Lucas Ocampos, respectively.
Gianluca Mancini received a red card in the compensated time for the second half.
Due to the coronavirus pandemic, the teams played for a ticket to the quarterfinals in one match, playing on a neutral field.
Thus, Sevilla reached the quarter finals, where they will play against the winner of the Olympiacos - Wolverhampton Wanderers match.
Earlier it was reported that Bayer beat the Rangers and reached the quarter finals of the Europa League.