The meeting, which took place at the Russian Railways Arena stadium in Moscow, ended with the victory of Atlético 2-0.
Goals in the match on account of João Felisch and Thomas Parti.
Lokomotiv dropped to third place in Group D. Juventus and Atlético, with four points each, are leading.
Earlier it was reported that Real Madrid tied with Brugge in the Champions League match, recouping from 0: 2.