The freelance journalist, who worked for McClatchy News, the Washington Post and Agence France-Presse (AFP) among others and covered the war in Syria, was kidnapped in August 2012 in Daraya, a suburb of Damascus, where the army had carried out a search operation.
Then 31 years old, he appeared in a video in September 2012, blindfolded.
But the identity of his captors remains unknown to this day and little information has been made public since his abduction.
On August 10, Mr. Biden said that the United States was "certain" that the journalist was "held by the Syrian regime".
“We have repeatedly asked the government of Syria to work with us to bring Austin home,” he added.
In a statement, the Syrian Foreign Ministry dismissed Mr Biden's "misleading, absurd and false statements" accusing "the Syrian government of kidnapping or arresting American citizens, including Austin Tice".
"The Syrian government denies having abducted or hidden any American citizen who entered its territory or who lived in areas under its authority," he added.
This is the first time that Syrian diplomacy has published a press release denying the detention of the American journalist.
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In 2020, then-US President Donald Trump sent Bashar al-Assad a personal message about the journalist.
He said he did not know if the reporter was still alive.
In 2018, US authorities announced a $1 million reward for anyone providing information that could lead to Mr Tice's release.
© 2022 AFP