Two Germans, four Indians and 16 Nepalese were on board the plane that crashed just 15 minutes after taking off from the city of Pokhara west of Kathmandu.
On Monday morning, the wreck was found and at lunch, rescue teams had arrived at the scene.
20 people were found dead while two people are still missing.
"There is very little chance of finding survivors," said Deo Chandra Lal Karna, a spokeswoman for Nepal's civil aviation authority, Reuters reports.
Difficult terrain, bad weather and lack of visibility made it difficult to search and rescue.
- There are very thick clouds in the area.
The search for bodies is ongoing, said Netra Prasad Sharma.
The plane was on its way to the mountain village of Jomsom, about a 20 minute flight away and a popular destination for hikers.
Nepal's aviation tourism has expanded greatly in recent years and climbers and hikers fly to places that are difficult to reach on foot.