OL will challenge the sixth in the Premier League in London on April 7, before hosting the Hammers on April 14 at Groupama stadium.
Jean-Michel Aulas' club, behind in the league, got the better of Porto in the previous round (1-0 then 1-1).
West Ham for its part brought down Sevilla FC, specialists in the event, with a goal scored in extra time by Ukrainian Andriy Yarmolenko (2-0 in the return after a 1-0 defeat in Spain).
The joy of the Lyonnais, qualified for the quarter-finals of the Europa League, despite their draw at home (1-1) against Porto, on March 17, 2022 at the Groupama Stadium in Décines-Charpieu JEAN-PHILIPPE KSIAZEK AFP
Former Stéphanois Kurt Zouma, now at West Ham, will find a taste for games against OL.
The Parisian Alphonse Areola, loaned to the London club, will also be traveling in the Rhône.
In the event of qualification, the Lyonnais will face the winner of the Barça-Frankfurt quarter.
The Spaniards start as favorites against the Germans, currently ninth in the Bundesliga, but the difficult qualification acquired against the Turks of Galatasaray (0-0 then 2-1) proves that the road to Seville, venue of the final, is not a long calm river.
Eintracht goalkeeper Kevin Trapp has bad memories of Camp Nou.
It was he who guarded the cage of Paris SG during the famous "remontada" (4-0 defeat in the first leg, 6-1 victory in the return) of 2017 in the Champions League.
In the other quarter-finals, the Germans of Leipzig will be opposed to the Italians of Atalanta Bergamo and the Portuguese of Braga, scorers of Monaco, will face the Scots of Glasgow Rangers.
© 2022 AFP