The immune system has a "memory" of the
coronavirus. If you have been infected with other coronaviruses, it will help speed up the human body to clear the new coronavirus.
International war "epidemic" operation
Science and Technology Daily, Beijing, November 11 (Reporter Zhang Mengran) An immunological study published on the 11th in the British "Nature" magazine pointed out that past exposure to other coronaviruses may increase the body's speed of clearing the new coronavirus because the immune system has " "Memory" can remember viral replication proteins that are highly conserved among different coronaviruses.
The results of the study show that this highly conserved protein can be used as a target for future vaccines against endemic diseases and new coronaviruses.
The study analyzed medical staff with a higher risk of exposure to the new coronavirus. Although these people had a negative test for new coronavirus infection or antibodies, there are signs that they have increased the memory T cell response to this conservative complex, indicating that They can quickly clear the new coronavirus.
Previous studies have shown that exposure to the coronavirus can produce memory T cells, which may be able to effectively attenuate the new coronavirus infection.
U.K. University College London scientist Mara Manny and colleagues hypothesized that since previously existing memory T cells can recognize this replication-transcription complex (RTC, a conserved structure involved in viral replication) proteins, these have previously been Some memory T cells may help quickly control the new coronavirus.
The research team believes that simulating the expansion of these cross-reactive T cells in vaccine design may be used to prevent various endemic diseases or emerging coronaviruses.
In this study, scientists analyzed samples of 58 medical staff from various hospitals in London, England.
In the first wave of the British epidemic, although these individuals were at high risk of exposure, no one tested positive for the new coronavirus infection.
The team of scientists compared the T cell response of the cohort with the medical staff in the control group who were laboratory-confirmed with a new coronavirus infection.
Compared to individuals who test positive, individuals who can escape infection seem to have a stronger T cell response, especially for this kind of RTC.