China News Service, September 27 (Reporter Chen Jing) A father used his own stem cells to give birth to twin sons suffering from rare inherited blood diseases through two peripheral blood stem cell collections.

  The Shanghai Children's Hospital told reporters on the 27th that the hospital had never encountered a special transplant case of one donor and two before.

  At the beginning of 2017, a pair of 3-year-old twin brothers, Xiaojie (brother) and Xiaoyan (brother) (both pseudonyms), both experienced intermittent nosebleeds.

After examination by the local hospital, it was found that the child's platelet counts were reduced, and the cause is unknown. After more than a year of immunization and symptomatic treatment, the platelet index has not been significantly improved.

In Shanghai Children's Hospital, after genetic testing for genetic diseases of the blood system, the two little brothers were diagnosed as having rare inherited blood diseases at the same time.

This means that if no stem cell transplantation is done, the brothers will rely on blood transfusions for life.

  After the child’s family accepted the transplant plan, the transplant team quickly took over the treatment of the twins. After a series of donor matching screenings, pre-transplant inspections and evaluations, the father of the twins was finally selected as the transplant donor.

Unlike usual, the transplant recipients this time are twins.

The transplant team has tailored a special transplant plan for the twins.

  Everything is ready, and the twins enter the transplant warehouse as planned.

With the joint efforts of doctors, nurses, twins and their families, they successfully passed the "pretreatment checkpoint" before hematopoietic stem cell transplantation.

On August 19, the child's father's peripheral blood stem cells were successfully transfused into Xiaojie's body; the next day, Xiaoyan also successfully transfused his father's peripheral blood stem cells.

  The hospital told reporters that the twin brothers had already escaped the fate of life-long blood transfusion.

The medical staff looked forward to the twins' return to campus and normal life with full confidence.

  It is reported that the Department of Hematology of Shanghai Children's Hospital successfully completed the first child autologous peripheral blood hematopoietic stem cell transplantation in 1998. As of September 2021, a total of more than 180 cases of various types of hematopoietic stem cell transplantation have been completed, with a 100% out-of-stock rate.