What are the vaccine side reactions you care about?

What are the characteristics of Delta and Lambda strains?

August 16 21:22

It is estimated that the new coronavirus has now been replaced by the mutant virus "Delta strain" in most parts of the country.

In addition, a new mutant virus called "Lambda strain" has also been found in the quarantine.


Mutant virus that appears one after another.

Above all, I summarized what kind of virus is about Delta strain and Lambda strain.

The side reaction of the vaccine you care about

First of all, the side reaction of the corona vaccine that is of concern, but how many have been reported?

According to the materials of the research group of the Ministry of Health, Labor and Welfare presented at the subcommittee on side reactions of vaccines on August 4, 2021, the main side reactions of Pfizer's vaccine are ▽ aching pain, people with soreness. 92.6% after the first inoculation, 89.5% after the second inoculation, ▽ 23.2% after the first inoculation, 68.9% after the second inoculation, ▽ headache for the first time 21.4% after inoculation, 53.1% after the second inoculation, ▽ Itching is 8.0% after the first inoculation, 11.9% after the second inoculation, ▽ Fever of 38 degrees or more is 0.9 after the first inoculation %, 21.3% after the second inoculation.



In addition, with the Moderna vaccine, there are many cases where side reactions occur after the second inoculation. , ▽ People with malaise were 26.8% after the first inoculation, 83.9% after the second inoculation, ▽ Headache was 17.4% after the first inoculation, 67.6% after the second inoculation, ▽ Itching However, it was 5.3% after the first inoculation, 13.7% after the second inoculation, 2.1% after the first inoculation, and 61.9% after the second inoculation.



As of July 25, 43 Pfizer vaccines and 3 Moderna were reported to be suspected of having myocarditis or pericarditis, which causes inflammation of the heart muscle and membrane, all of which are 1 million. The ratio was 1.1 per person.

The Ministry of Health, Labor and Welfare said, "Since the two types of vaccines are inoculated at different ages, it is not possible to make a simple comparison." I will proceed.



Also, according to the US Centers for Disease Control and Prevention (CDC), side reactions usually disappear within a few days after vaccination.



Most were mild to moderate, with few side reactions affecting daily life.

"Delta stock" is the current threat

According to the WHO (World Health Organization), the Delta strain was first reported in India in October 2020 and is believed to be one of the causes of the explosive spread in India since April 2021.



WHO ranks it as the most vigilant, VOC (Variant of Concern), with 142 countries and regions reporting Delta strains as of August 10, 2021.

It is highly infectious, about twice as much as the conventional new coronavirus, and about 1.5 times as much as the alpha strain that spread in the fourth wave of the spread of infection in Japan.



The Delta strain is also positioned as a VOC (Variant of Concern) by the National Institute of Infectious Diseases in Japan.



Research is underway in each country to determine whether or not the infection is likely to become severe, but WHO says that the risk of hospitalization is increasing.



A study presented in August 2021 by a group at the University of Toronto in Canada, which had not yet been peer-reviewed, analyzed 200,000 patients with the new corona and found that the Delta strain was a conventional virus. The risk of hospitalization was 2.08 times, the risk of needing an ICU was 3.34 times, and the risk of dying was 2.32 times.



WHO said laboratory-level studies have shown that vaccines produce less neutralizing antibodies against Delta strains.

"Lambda stock" has many unknown parts

According to WHO, the mutant virus Lambda strain was first reported in Peru, South America in August 2020, and has spread mainly to South American countries such as Peru, Chile, and Ecuador.



As of August 15, 2021, 34 countries have reported lambda strains on the website "GISAID" that registers the gene sequences of new coronaviruses around the world, but most of the registrations have been made in the last four weeks. Is from Chile in South America.



WHO has positioned it as a VOI (Variant of Concern) due to the possibility that it is more infectious than conventional viruses and the mutation that makes it difficult for neutralizing antibodies that suppress the action of the virus to work, but at present, Delta It is not as widespread as the mutant virus, which is positioned as a VOC (variant of concern) such as strains and alpha strains.

About Lambda Strains The National Institute of Infectious Diseases has not yet positioned it as a VOC (Variant of Concern) or VOI (Notable Mutant).



Lambda strains are often unknown about their infectivity and severity in the event of infection, and WHO says it needs to further investigate whether measures to control infection and the effectiveness of vaccines will be affected.



Lambda strains were actually found earlier than Delta strains, but the speed of spread of infection is faster with Delta strains than with Lambda strains, which is a more pressing issue in each country.

Does the vaccine work for Delta strains?

Studies have emerged from various countries that the vaccines currently inoculated in Japan are also highly effective against Delta strains.

Among them, in July 2021, the international medical journal "New England Journal of Medicine" published a study by a group such as the British health authorities and the University of London, and found that the vaccine's preventive effect on the delta strain was found by Pfizer. 35.6% after one vaccination, 88.0% after two vaccinations, 30.0% after one vaccination with AstraZeneca vaccine, and 67.0% after two vaccinations.



According to the research group, "after two inoculations, a high preventive effect was also seen on the Delta strain."

In addition, according to the results of a study of 77,000 people published as a pre-reviewed paper by groups such as the May York Clinic in the United States, the effect of preventing infection was effective in July 2021 when the Delta strain spread widely. The Pfizer vaccine was 42% and the Moderna vaccine was 76%, which was lower than before, but the effect of preventing hospitalization was 75% for the Pfizer vaccine and 81% for the Moderna vaccine, both of which remained high. I have done it.