15 minutes!
I independently research and develop testing products to quickly and accurately identify delta
Our reporter Liu Zhiwei Wu Chunxin Correspondent Yan Tianfeng Song Zhihui
On August 10, another batch of new crown testing products independently developed by Liangzhun Industrial Co., Ltd., an incubator of Wuhan Optoelectronics Industrial Research Institute, was shipped to Morocco. This is the fifth time that Liangzhun exported new crown testing products to this country this year.
This batch of testing products can quickly and accurately identify Delta mutant strains within 15 minutes.
Since receiving a number of overseas orders at the beginning of this year, the relevant products of Liangzhun have been exported to the Moroccan and Sri Lankan markets. Its overall new crown detection program has helped nearly a million people in the local area to complete the new crown virus detection and antibody screening.
At the end of July, the high-throughput new crown antigen detection product independently developed by Liangzhun Company passed the inspection of the Guangdong Medical Device Inspection Institute of the State Food and Drug Administration.
The test report shows that the specificity and sensitivity of the Quantitative New Coronary Antigen Detection Kit are close to 100%, and the lower limit of detection concentration reaches the level of 23.4TCID50/mL.
Within 15 minutes, high-throughput delta variant new coronavirus detection can be achieved, and rapid screening of asymptomatic infections can be completed.
"We have successfully applied Nano SPR technology in the new crown detection field. The detection products based on the new generation of Nano SPR chip can collect signal data from multiple dimensions, amplify the signal by more than a thousand times, and obtain higher detection sensitivity and lower detection sensitivity. The lower limit of molecular concentration detection has received good feedback in both scientific research and clinical markets.” said the relevant person in charge of Quanquan.
According to reports, Liangzhun has been committed to the world's leading research and development of biochip micro-measurement technology for a long time.
Since the outbreak of the new crown epidemic, the company has responded to the national exhibition to fight against the epidemic, and has successively developed and produced a number of new crown antigen/antibody detection products, and its work and efforts have been recognized by the Ministry of Science and Technology.
At the beginning of this year, Liangzhun conducted a large number of clinical comparison experiments in overseas markets.
Nano SPR and ELISA were used to detect 139 clinical samples. Through X2 test and analysis, there was no difference in the results of the two methods.
And with Nano SPR, the test can be completed in about 15 minutes, while it takes more than 2 hours to complete the traditional ELISA test.
Clinical experiments show that, compared with conventional detection methods, Quantitative Nano SPR has the advantages of high sensitivity, high specificity, high detection rate, and high negative/positive coincidence rate.
As of May this year, Quanquan has obtained CE certification for 4 new crown products and entered the whitelist of the Ministry of Commerce for export of anti-epidemic materials.
The company's other core product, SARS-CoV-2 neutralizing antibody detection kit, has been clinically tested in many domestic medical institutions such as Wuhan Union Hospital, Hubei Center for Disease Control and Prevention, Fudan University Laboratory, etc. The results are gratifying and are now sold. Morocco and many other countries.
"Science and technology wars against the epidemic, Hubei has full horsepower, and measurement is one of the representatives." said Chen Zicai, director of the Achievement and Regional Division of Hubei Science and Technology Department. There are 63 business incubators and 61 national-level makerspaces. With the help of a comprehensive full-chain technology entrepreneurship service system, a number of high-level self-developed anti-epidemic products continue to emerge, providing strong scientific and technological support for the frontline war epidemic.
"At this stage, we are conducting concentrated research on the source of the new crown epidemic in many places in China-Delta mutant strains." According to the relevant person in charge of Quanquan, Delta mutant strains have not changed much in the antigen structure, so at the nucleic acid level. Specific recognition is the key to distinguishing virus strains.
The person in charge said that at present, they are developing related room temperature nucleic acid recognition amplification and amplification systems. With the aid of the signal amplification platform of Nano SPR, nucleic acid amplification in a short period of time can be amplified and recognized by the chip system.