The march, which usually takes place in early May, has been postponed twice, but was finally given the green light by the country's now ousted Prime Minister Benjamin Netanyahu.
The march will take place less than a month into the ceasefire between Israel and Hamas - which has promised to react if the march ends.
There is a risk of collisions.
- It has been a quiet week so far but Jerusalem is and will remain a powder keg and it will also be a first stress test for Israel's new government, says Anders Persson.