China News Service, March 26 (Chen Jing and Xu Lanqing) Among the chronically ill patients in China, there are a large number of people suffering from cardiovascular diseases.
How to better treat cardiovascular diseases has become an urgent problem to be solved.
The reporter learned on the 26th that after 15 years of research and development, a new generation of fully degradable stents developed by a team led by Ge Junbo, academician of the Chinese Academy of Sciences and director of the Shanghai Institute of Cardiovascular Diseases, has attracted much attention.
In an interview with reporters that day, well-known expert in cardiology, Professor Sun Guigui said that the fully degradable stent can change the blood vessel from "recanalization" to "remodeling", effectively inhibit the stent intimal hyperplasia, and greatly reduce in-stent restenosis and re-interventional surgery The rate of occurrence.
It is understood that heart stent surgery is a common method for the treatment of coronary heart disease, but the metal stent must remain in the body forever after implantation, and the patient needs to take medicine for a long time, which has become a kind of "heart disease" for stent patients.
Scientific research has found that, in fact, the coronary stent does not need to be "placed" in the body for a lifetime. Its "service" cycle is 6 months after the stent is implanted in the coronary artery, after which it can "retire" and allow the blood vessel to recover. The original look.
It is reported that the biodegradable stent developed by the team of Academician Ge Junbo has experienced 15 years of research and development, scientific research and clinical research follow-up, and has independent intellectual property rights in China.
After being implanted in the body for a period of time, this XinSorb biodegradable stent can mechanically support the narrowed coronary blood vessels and release drugs to prevent restenosis. It then slowly degrades and is completely absorbed by the tissues, and finally the vascular structure and function are completely restored.
Compared with traditional permanent metal stents, fully degradable stents are made of biodegradable or absorbable materials, and have good tissue compatibility and biodegradability. After the degradable stent is implanted in the stenosis of the blood vessel, it is both It can effectively expand blood vessels in the early stage, and can be gradually degraded.
The degradation products can be eliminated from the body through metabolism or absorbed by the body without affecting the long-term vascular function.
Professor Sun Baogui believes that the promotion and use of biodegradable (absorbable) stents will definitely bring new development opportunities for cardiac interventional therapy and will benefit more cardiovascular patients.
Professor Sun Baogui told reporters that a 66-year-old male patient with coronary heart disease successfully implanted two fully degradable stents in his hospital, and the postoperative effect was good.
Cardiology expert Xu Dongjin told reporters that the patient’s left coronary circumflex artery was 100% occluded, and the proximal and distal right coronary segments had 80-90% and 75-85% stenosis, respectively. If surgery is not performed in time, it will lead to myocardial stenosis. Infarction, life-threatening.
Another 47-year-old male patient successfully implanted a fully degradable stent and his chest tightness and chest pain disappeared.
Professor Sun Baogui told reporters that a year after the fully degradable stent is placed in the blood vessel, it can complete the remodeling of the blood vessel, and will gradually degrade, and eventually become water and carbon dioxide completely absorbed by the body, and the patient does not need to take medicine for life.
At the same time, the fully degradable stent has a lower probability of restenosis than traditional stents due to its degradability; the fully degradable stent can be completely dissolved 2 to 3 years after being placed, and it can be repeatedly inserted when the blockage occurs again. Get treatment.
After the stent is completely degraded, the area of the blood vessel lumen will increase, and the incidence of postoperative angina will be lower.
However, Professor Sun Baogui also bluntly stated that although the fully degradable stent has so many benefits, due to the difficulty of operation and the strict requirements of the indications, patients must follow the doctor's advice.
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